SYNTHETIC THERAPEUTIC AGENTS
نویسندگان
چکیده
منابع مشابه
Synthetic oligonucleotides as therapeutic agents.
Currently there is much excitement in certain quarters about antisense oligonucleotides, both as the drugs of the future for treatment of cancer and viral infections, most notably AIDS, and also as genetic tools for generating mutant phenocopies without genomic mutation in investigations of mammalian gene function. The extent of this excitement is reflected in the proliferation of antisense bio...
متن کاملA Comparative Study upon the Therapeutic Indices of Some Natural and Synthetic Anti-inflammatory Agents
Objective(s) The aim of the present study was to compare the therapeutic indices of several agents used in treatment of inflammatory conditions which included: Vitamin E, hydro-alcoholic extracts of Glycyrrhiza glabra, Matricaria aurea, dexamethasone, piroxicam and diclofenac using Wehi-164 fibrosarcoma cells. Materials and Methods Cytotoxicity evaluation was based on vital dye exclusion ass...
متن کاملa comparative study upon the therapeutic indices of some natural and synthetic anti-inflammatory agents
objective(s) the aim of the present study was to compare the therapeutic indices of several agents used in treatment of inflammatory conditions which included: vitamin e, hydro-alcoholic extracts of glycyrrhiza glabra, matricaria aurea, dexamethasone, piroxicam and diclofenac using wehi-164 fibrosarcoma cells. materials and methods cytotoxicity evaluation was based on vital dye exclusion assay....
متن کاملTrapping of DNA-reactive metabolites of therapeutic or carcinogenic agents by carbon-14-labeled synthetic polynucleotides.
Many substances which do not react with DNA directly are metabolized into important DNA-modifying intermediates. We have devised a method for trapping these intermediates with 14C-labeled nucleosides contained in a synthetic polynucleotide. The polynucleotide structure protects the labeled nucleoside from metabolism; thus, it is unaltered when the polymer is incubated with a drug-metabolizing s...
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ژورنال
عنوان ژورنال: BMJ
سال: 1924
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.3297.413